Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371489 | 0.90 | KDM4E (0.54) | KDM4ETSHRPTK2BMAPTKMT2A | |
| SCHEMBL697780 | 0.77 | KDM4E (0.54) | KDM4EMAPTKMT2AMEN1LMNA | |
| SCHEMBL7375606 | 0.77 | ACLY (0.46) | TSHRMAPTKMT2AMEN1LMNA | |
| SCHEMBL10212480 | 0.75 | KDM4E (0.55) | KDM4EMAPTKMT2AMEN1LMNA | |
| SCHEMBL7371484 | 0.74 | ACLY (0.53) | KDM4EMAPTKMT2AMEN1LMNA | |
| SCHEMBL6926045 | 0.71 | MAPT (0.67) | KDM4ETSHRPTK2BMAPTKMT2A | |
| SCHEMBL29087625 | 0.71 | KDM4E (0.52) | KDM4EMAPTKMT2AMEN1LMNA | |
| SCHEMBL7375039 | 0.70 | PTPN2 (0.56) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL7374089 | 0.70 | CHEK2 (0.55) | MAPTKMT2AMEN1LMNATP53 | |
| SCHEMBL7370125 | 0.69 | MAPT (0.49) | MAPTKMT2AMEN1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001074786-A1 | HETEROBIARYLSULPHONAMIDES AND THEIR USE AS PDE 7 INHIBITORS | DARWIN DISCOVERY LIMITED (GB) | 2001-10-11 | — | — | WO | disclosed |