Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CCR9 | P51686 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 2/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371489 | 0.85 | KDM4E (0.54) | ACLYMAPTMEN1LMNAKMT2A | |
| SCHEMBL7372718 | 0.83 | MAPT (0.44) | MAPTMEN1LMNAKMT2ATP53 | |
| SCHEMBL7377092 | 0.81 | CCR9 (0.51) | ACLYMAPTMEN1LMNAKMT2A | |
| SCHEMBL7371484 | 0.79 | ACLY (0.53) | ACLYMAPTMEN1LMNAKMT2A | |
| SCHEMBL7374089 | 0.78 | CHEK2 (0.55) | MAPTMEN1LMNAKMT2ATP53 | |
| SCHEMBL7367124 | 0.78 | CCR9 (0.51) | ACLYMAPTMEN1LMNAKMT2A | |
| SCHEMBL6840289 | 0.78 | PIN1 (0.56) | MAPTMEN1KMT2ATP53HPGD | |
| SCHEMBL7372020 | 0.77 | KDM4E (0.46) | MAPTMEN1LMNAKMT2ATP53 | |
| SCHEMBL7372057 | 0.73 | KDM4E (0.64) | ACLYMAPTMEN1LMNAKMT2A | |
| SCHEMBL6840181 | 0.73 | TNKS (0.54) | KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001074786-A1 | HETEROBIARYLSULPHONAMIDES AND THEIR USE AS PDE 7 INHIBITORS | DARWIN DISCOVERY LIMITED (GB) | 2001-10-11 | — | — | WO | claimed |
| WO-2001074786-A1 | HETEROBIARYLSULPHONAMIDES AND THEIR USE AS PDE 7 INHIBITORS | DARWIN DISCOVERY LIMITED (GB) | 2001-10-11 | — | — | WO | disclosed |