Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.53 |
| ▸ | MMP9 | P14780 | 8/20 | 0.53 |
| ▸ | MMP12 | P39900 | 12/20 | 0.51 |
| ▸ | MMP13 | P45452 | 10/20 | 0.51 |
| ▸ | MMP8 | P22894 | 4/20 | 0.50 |
| ▸ | MMP14 | P50281 | 4/20 | 0.50 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344997 | 0.88 | MMP12 (0.55) | MMP2MMP9MMP12MMP13MMP8 | |
| SCHEMBL6416338 | 0.87 | MMP2 (0.70) | MMP2MMP9MMP12MMP13MMP14 | |
| SCHEMBL7353718 | 0.86 | MMP2 (0.54) | MMP2MMP9MMP12MMP13MMP8 | |
| SCHEMBL6420328 | 0.84 | MMP2 (0.66) | MMP2MMP9MMP12MMP13MMP14 | |
| SCHEMBL7343612 | 0.83 | MMP2 (0.51) | MMP2MMP9MMP12MMP13MMP8 | |
| SCHEMBL7354362 | 0.83 | MMP12 (0.54) | MMP2MMP9MMP12MMP13MMP8 | |
| SCHEMBL7352006 | 0.81 | MMP12 (0.52) | MMP2MMP9MMP12MMP13MMP8 | |
| SCHEMBL7345951 | 0.81 | MMP12 (0.50) | MMP2MMP9MMP12MMP13MMP8 | |
| SCHEMBL7352548 | 0.81 | MMP12 (0.53) | MMP2MMP9MMP12MMP13MMP8 | |
| SCHEMBL7352152 | 0.81 | MMP12 (0.53) | MMP2MMP9MMP12MMP13MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929542-A1 | COMPOUNDS FOR AND A METHOD OF INHIBITING MATRIX METALLOPROTEINASES | WARNER-LAMBERT COMPANY (US) | 1999-07-21 | — | — | EP | claimed |
| WO-1998009957-A1 | COMPOUNDS FOR AND A METHOD OF INHIBITING MATRIX METALLOPROTEINASES | WARNER-LAMBERT COMPANY (US) | 1998-03-12 | — | — | WO | claimed |