Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 14/20 | 0.54 |
| ▸ | PPARD | Q03181 | 5/20 | 0.54 |
| ▸ | PPARG | P37231 | 4/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.48 |
| ▸ | PDE5A | O76074 | 3/20 | 0.47 |
| ▸ | PDE6D | O43924 | 1/20 | 0.47 |
| ▸ | PDE6A | P16499 | 1/20 | 0.47 |
| ▸ | PDE6G | P18545 | 1/20 | 0.47 |
| ▸ | PDE6B | P35913 | 1/20 | 0.47 |
| ▸ | PDE6C | P51160 | 1/20 | 0.47 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360754 | 0.86 | PPARA (0.49) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL7372290 | 0.86 | PPARA (0.53) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL6941879 | 0.85 | PPARA (0.52) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL6943273 | 0.83 | PPARA (0.55) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL27557551 | 0.81 | GAA (0.49) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL7368352 | 0.80 | PDE5A (0.50) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL7368350 | 0.80 | PDE5A (0.50) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL7369160 | 0.80 | PPARA (0.47) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL7571103 | 0.79 | CCR2 (0.47) | PPARAPPARDPPARGPDE5A | |
| SCHEMBL7692582 | 0.79 | CCR2 (0.47) | PPARAPPARDPPARGPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |