Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ARG1 | P05089 | 3/20 | 0.46 |
| ▸ | ARG2 | P78540 | 2/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 3/20 | 0.40 |
| ▸ | ANPEP | P15144 | 2/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373388 | 1.00 | SLC7A5 (0.47) | SLC7A5LMNABLMARG1ARG2 | |
| SCHEMBL7375831 | 0.93 | EPHX1 (0.49) | SLC7A5LMNABLMARG1ARG2 | |
| SCHEMBL13995144 | 0.93 | EPHX1 (0.53) | SLC7A5LMNABLMARG1ARG2 | |
| SCHEMBL7375829 | 0.93 | EPHX1 (0.49) | SLC7A5LMNABLMARG1ARG2 | |
| SCHEMBL7307570 | 0.91 | EPHX1 (0.56) | LMNABLMARG1ARG2EPHX1 | |
| SCHEMBL17152290 | 0.88 | ARG1 (0.42) | SLC7A5LMNABLMARG1ARG2 | |
| SCHEMBL17152281 | 0.87 | KDM4E (0.43) | SLC7A5LMNABLMARG1ARG2 | |
| SCHEMBL17152405 | 0.84 | KDM4E (0.48) | LMNABLMARG1ARG2SMYD3 | |
| SCHEMBL21555142 | 0.84 | EPHX1 (0.42) | SLC7A5LMNABLMARG1ARG2 | |
| SCHEMBL17152503 | 0.84 | PIK3CD (0.42) | SLC7A5LMNABLMARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777646-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996006074-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-02-29 | — | — | WO | disclosed |