Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367239 | 0.88 | ITGB3 (0.39) | ITGB3ITGA2B | |
| SCHEMBL7835225 | 0.86 | ITGB3 (0.32) | ITGB3ITGA2B | |
| SCHEMBL7369874 | 0.78 | KDM1A (0.34) | MAOAMAOBF2 | |
| SCHEMBL7793872 | 0.78 | KDM1A (0.34) | MAOAMAOBF2 | |
| SCHEMBL8121928 | 0.77 | F2 (0.30) | F2 | |
| SCHEMBL8124835 | 0.75 | MASP2 (0.31) | — | |
| SCHEMBL8129068 | 0.74 | KDM1A (0.31) | — | |
| SCHEMBL7444463 | 0.73 | ITGB3 (0.49) | ITGB3ITGA2B | |
| SCHEMBL7374127 | 0.72 | ITGB3 (0.38) | ITGB3ITGA2B | |
| SCHEMBL9093436 | 0.72 | ITGB3 (0.47) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-B1 | ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | DU PONT PHARM CO (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1995014683-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-06-01 | — | — | WO | disclosed |