SCHEMBL7373753

SCHEMBL7373753

CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)c1ncc[nH]1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
REN P00797 19/20 0.63
PGC P20142 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7314662 0.90 REN (0.55) RENPGC
SCHEMBL7309924 0.90 REN (0.55) RENPGC
Acetic Acid SCHEMBL7326759 0.89 REN (0.54) RENPGC
SCHEMBL7368073 0.88 REN (0.58) RENPGC
SCHEMBL9725895 0.84 REN (0.61) REN
SCHEMBL9725900 0.84 REN (0.61) REN
SCHEMBL7329655 0.84 REN (0.67) REN
SCHEMBL9725871 0.84 REN (0.61) REN
SCHEMBL9725876 0.84 REN (0.61) REN
SCHEMBL7434868 0.82 REN (0.63) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0231919-A2 N-Heterocyclic alcohol renin inhibitors E.R. Squibb & Sons, Inc. (US) 1987-08-12 EP disclosed