Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | STK25 | O00506 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6171008 | 0.86 | DHPS (0.46) | DHPSTAS1R3TAS1R1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7364951 | 0.84 | F10 (0.40) | DHPSSMN1; SMN2ALDH1A1LMNAMAPK1 | |
| SCHEMBL7372778 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1LMNAMAPK1STK25 | |
| SCHEMBL6172985 | 0.77 | DHPS (0.53) | DHPSTAS1R3TAS1R1ALDH1A1MAPK11 | |
| SCHEMBL6172921 | 0.75 | ESR1 (0.56) | DHPSALDH1A1MAPK11MAPK14BTK | |
| SCHEMBL6170574 | 0.70 | F10 (0.41) | DHPSSMN1; SMN2ALDH1A1LMNAMAPK1 | |
| SCHEMBL13483891 | 0.69 | ESR1 (0.76) | DHPSSMN1; SMN2BTKESR1MAPT | |
| SCHEMBL6170923 | 0.69 | PDE4A (0.41) | DHPSSMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL6167952 | 0.67 | DHPS (0.55) | DHPSMAPK11MAPK14BTKESR1 | |
| SCHEMBL5221860 | 0.67 | F10 (0.83) | SMN1; SMN2ALDH1A1LMNAMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019045-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-1019045-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999000128-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |