Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | STK25 | O00506 | 1/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
| ▸ | DHPS | P49366 | 2/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6170923 | 0.86 | PDE4A (0.41) | F10ALDH1A1SMN1; SMN2LMNAPDE4A | |
| SCHEMBL7374264 | 0.84 | DHPS (0.42) | F10ALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL6170844 | 0.78 | SERPINE1 (0.48) | F10ALDH1A1SMN1; SMN2LMNAPDE4A | |
| SCHEMBL7372778 | 0.78 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2LMNAMAPK1STK25 | |
| SCHEMBL6170574 | 0.77 | F10 (0.41) | F10ALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL6171008 | 0.69 | DHPS (0.46) | F10ALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL6170659 | 0.67 | DHPS (0.45) | ALDH1A1SMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL31396280 | 0.67 | F10 (0.57) | F10PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5221860 | 0.65 | F10 (0.83) | F10ALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8307530 | 0.63 | PDE4A (0.52) | F10PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999000128-A9 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-08-05 | — | — | WO | disclosed |