Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP1 | P63208 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22097989 | 0.89 | KMT2A (0.60) | L3MBTL1KMT2AKDM1AMAOBKCNA3 | |
| SCHEMBL22097772 | 0.89 | KMT2A (0.60) | L3MBTL1KMT2AKDM1AMAOBKCNA3 | |
| SCHEMBL1851171 | 0.88 | KMT2A (0.91) | L3MBTL1KMT2AUSP2OPRK1LMNA | |
| SCHEMBL9308794 | 0.85 | KMT2A (0.61) | L3MBTL1KMT2AKDM1AMAOBEPHX2 | |
| SCHEMBL8869835 | 0.85 | KMT2A (0.61) | L3MBTL1KMT2AKDM1AMAOBEPHX2 | |
| SCHEMBL4794886 | 0.85 | L3MBTL1 (1.00) | L3MBTL1KMT2AUSP2OPRK1LMNA | |
| SCHEMBL20967988 | 0.85 | L3MBTL1 (1.00) | L3MBTL1KMT2AUSP2OPRK1LMNA | |
| SCHEMBL29410965 | 0.85 | L3MBTL1 (1.00) | L3MBTL1KMT2AUSP2OPRK1LMNA | |
| SCHEMBL8566009 | 0.85 | KMT2A (0.61) | L3MBTL1KMT2AKDM1AMAOBEPHX2 | |
| SCHEMBL16022317 | 0.85 | KMT2A (0.61) | L3MBTL1KMT2AKDM1AMAOBEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417698-B1 | Amino acid derivatives having renin-inhibiting activity, process for their preparation, agents containing them, and their use | HOECHST AG (DE) | 1996-03-13 | — | — | EP | disclosed |
| US-5374731-A | Treatment of high blood pressure, congestive heart failure and viral disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-12-20 | — | — | US | disclosed |