Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308794 | 1.00 | KMT2A (0.61) | KMT2AL3MBTL1MAPTKDM1AMAOB | |
| SCHEMBL16022317 | 1.00 | KMT2A (0.61) | KMT2AL3MBTL1MAPTKDM1AMAOB | |
| SCHEMBL8869835 | 1.00 | KMT2A (0.61) | KMT2AL3MBTL1MAPTKDM1AMAOB | |
| SCHEMBL30843796 | 0.89 | KMT2A (0.60) | KMT2AL3MBTL1MAPTKDM1AMAOB | |
| SCHEMBL7919861 | 0.89 | KMT2A (0.60) | KMT2AL3MBTL1MAPTKDM1AMAOB | |
| SCHEMBL12381737 | 0.89 | KMT2A (0.60) | KMT2AL3MBTL1MAPTKDM1AMAOB | |
| SCHEMBL28529567 | 0.89 | KMT2A (0.60) | KMT2AL3MBTL1MAPTKDM1AMAOB | |
| SCHEMBL13841915 | 0.88 | KMT2A (0.61) | KMT2AL3MBTL1MAPTKDM1AMAOB | |
| SCHEMBL2821018 | 0.88 | KMT2A (0.61) | KMT2AL3MBTL1MAPTKDM1AMAOB | |
| SCHEMBL13841916 | 0.86 | KMT2A (0.59) | KMT2AL3MBTL1KDM1AMAOBEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871628-A1 | QUINOLIZINONE TYPE COMPOUNDS | Abbott Laboratories (US) | 1998-10-21 | — | — | EP | disclosed |