Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 6/20 | 0.68 |
| ▸ | PRCP | P42785 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8853554 | 0.88 | PNMT (0.71) | PNMTPRCPOPRM1OPRL1 | |
| SCHEMBL8853548 | 0.88 | PNMT (0.71) | PNMTPRCPOPRM1OPRL1 | |
| SCHEMBL20554026 | 0.85 | PNMT (0.67) | PNMTPRCPOPRM1OPRL1 | |
| SCHEMBL11388285 | 0.81 | PNMT (0.64) | PNMTPRCP | |
| SCHEMBL8783405 | 0.81 | PNMT (0.64) | PNMTPRCP | |
| SCHEMBL25377947 | 0.81 | PNMT (1.00) | PNMT | |
| SCHEMBL6847135 | 0.81 | PNMT (1.00) | PNMT | |
| SCHEMBL31263935 | 0.81 | PNMT (1.00) | PNMT | |
| SCHEMBL3129926 | 0.79 | PNMT (0.59) | PNMTPRCP | |
| SCHEMBL172636 | 0.79 | PNMT (0.69) | PNMTPRCPOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604186-B1 | Inhibitors of HIV protease useful for the treatment of aids | LILLY CO ELI (US) | 1997-01-22 | — | — | EP | disclosed |
| US-5491166-A | ENZYME INHIBITORS, VIRICIDES | ELI LILLY AND COMPANY (US) | 1996-02-13 | — | — | US | disclosed |
| EP-0604186-A1 | Inhibitors of HIV protease useful for the treatment of aids | ELI LILLY AND COMPANY (US) | 1994-06-29 | — | — | EP | disclosed |