Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 7/20 | 0.71 |
| ▸ | PRCP | P42785 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8853548 | 1.00 | PNMT (0.71) | PNMTPRCPOPRM1OPRL1ADRA2A | |
| SCHEMBL8783405 | 0.88 | PNMT (0.64) | PNMTPRCP | |
| SCHEMBL7374355 | 0.88 | PNMT (0.68) | PNMTPRCPOPRM1OPRL1 | |
| SCHEMBL11388285 | 0.88 | PNMT (0.64) | PNMTPRCP | |
| SCHEMBL3129926 | 0.85 | PNMT (0.59) | PNMTPRCP | |
| SCHEMBL13453377 | 0.85 | PNMT (0.69) | PNMTPRCPOPRM1OPRL1ADRA2A | |
| SCHEMBL172636 | 0.85 | PNMT (0.69) | PNMTPRCPOPRM1OPRL1ADRA2A | |
| SCHEMBL14355729 | 0.85 | PNMT (0.69) | PNMTPRCPOPRM1OPRL1ADRA2A | |
| SCHEMBL3127955 | 0.84 | PNMT (0.57) | PNMTPRCPOPRM1OPRL1ADRA2A | |
| SCHEMBL25377947 | 0.83 | PNMT (1.00) | PNMTADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670675-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1997-09-23 | — | — | US | disclosed |