SCHEMBL7374483

SCHEMBL7374483

Nc1ccnc2cc(CN3CC[C@H](N)C3=O)ccc12

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F10 P00742 16/20 0.40
NR4A2 P43354 1/20 0.40
SOS2 Q07890 1/20 0.40
F2 P00734 1/20 0.36
EHMT2 Q96KQ7 1/20 0.35
EHMT1 Q9H9B1 1/20 0.35
NCF1 P14598 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7921783 1.00 F10 (0.40) F10NR4A2SOS2F2EHMT2
SCHEMBL6224794 1.00 F10 (0.40) F10NR4A2SOS2F2EHMT2
Hydrochloric Acid SCHEMBL6221646 0.99 F10 (0.40) F10NR4A2SOS2F2EHMT2
Hydrochloric Acid SCHEMBL6221643 0.99 F10 (0.40) F10NR4A2SOS2F2EHMT2
Hydrochloric Acid SCHEMBL7539536 0.99 F10 (0.40) F10NR4A2SOS2F2EHMT2
Hydrochloric Acid SCHEMBL7539533 0.99 F10 (0.40) F10NR4A2SOS2F2EHMT2
Trifluoroacetic Acid SCHEMBL7923392 0.91 F10 (0.36) F10NR4A2SOS2F2
SCHEMBL7921805 0.91 F10 (0.42) F10NR4A2F2EHMT2EHMT1
SCHEMBL7921780 0.84 MET (0.40) F10NR4A2SOS2F2
SCHEMBL6224791 0.84 MET (0.40) F10NR4A2SOS2F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1086099-A4 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARM PROD INC (US) 2002-01-02 EP disclosed
EP-1086099-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS Aventis Pharmaceuticals Products Inc. (US) 2001-03-28 EP disclosed
WO-1999062904-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-12-09 WO disclosed