Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 9/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 9/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | PROC | P04070 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6224791 | 1.00 | MET (0.40) | METF10NR4A2SOS2GRM2 | |
| Trifluoroacetic Acid SCHEMBL7915310 | 0.93 | MET (0.40) | METF10GRM2NR1I2KCNH2 | |
| Trifluoroacetic Acid SCHEMBL7923391 | 0.93 | MET (0.40) | METF10GRM2NR1I2KCNH2 | |
| SCHEMBL7921803 | 0.91 | SMYD3 (0.40) | METF10NR4A2PLATPROC | |
| Trifluoroacetic Acid SCHEMBL7220554 | 0.85 | MET (0.38) | METF10NR4A2GRM2PLAT | |
| SCHEMBL6221508 | 0.85 | F10 (0.49) | F10 | |
| SCHEMBL7374483 | 0.84 | F10 (0.40) | F10NR4A2SOS2F2 | |
| SCHEMBL7921783 | 0.84 | F10 (0.40) | F10NR4A2SOS2F2 | |
| SCHEMBL6224794 | 0.84 | F10 (0.40) | F10NR4A2SOS2F2 | |
| Hydrochloric Acid SCHEMBL7539533 | 0.83 | F10 (0.40) | F10NR4A2SOS2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281227-B1 | INHIBITORS OF THE ACTIVITY OF FACTOR XA. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-08-28 | — | — | US | disclosed |