Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ME3 | Q16798 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374701 | 1.00 | ME3 (0.51) | ME3ALDH1A1ABL1MAPTSMN1; SMN2 | |
| SCHEMBL7374695 | 1.00 | ME3 (0.51) | ME3ALDH1A1ABL1MAPTSMN1; SMN2 | |
| SCHEMBL533096 | 0.83 | ALDH1A1 (0.62) | ME3ALDH1A1ABL1MAPTSMN1; SMN2 | |
| SCHEMBL7371765 | 0.81 | ME3 (0.54) | ME3ALDH1A1ABL1MAPTSMN1; SMN2 | |
| Acetic Acid SCHEMBL7374818 | 0.80 | ALDH1A1 (0.55) | ME3ALDH1A1ABL1MAPTITGB3 | |
| SCHEMBL8141352 | 0.79 | ME3 (0.52) | ME3ALDH1A1ABL1MAPTSMN1; SMN2 | |
| Acetic Acid SCHEMBL8143556 | 0.77 | ME3 (0.55) | ME3ALDH1A1ABL1MAPTSMN1; SMN2 | |
| Acetic Acid SCHEMBL8135057 | 0.76 | ME3 (0.52) | ME3ALDH1A1ABL1MAPTSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL7376343 | 0.75 | ME3 (0.48) | ME3ALDH1A1ABL1MAPTSMN1; SMN2 | |
| Acetic Acid SCHEMBL7375335 | 0.74 | ME3 (0.52) | ME3ALDH1A1ABL1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069143-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-30 | — | — | US | disclosed |
| EP-0885213-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0885213-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997025323-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-17 | — | — | WO | disclosed |