SCHEMBL7375016

SCHEMBL7375016

C=CCNC(=O)CCC(N)=O

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.65
TSHR P16473 2/20 0.65
MAPT P10636 1/20 0.65
FAAH O00519 1/20 0.53
ALDH1A1 P00352 2/20 0.46
HPGD P15428 3/20 0.41
HTT P42858 2/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.39
CASP3 P42574 1/20 0.38
KDM4E B2RXH2 1/20 0.38
RAB9A P51151 2/20 0.36
GLA P06280 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10898374 0.89 TSHR (0.83) SMN1; SMN2TSHRMAPTFAAHALDH1A1
SCHEMBL1958588 0.89 SMN1; SMN2 (0.81) SMN1; SMN2TSHRMAPTFAAHALDH1A1
SCHEMBL4068835 0.82 SMN1; SMN2 (0.58) SMN1; SMN2TSHRMAPTFAAHALDH1A1
SCHEMBL3459599 0.80 SMN1; SMN2 (0.68) SMN1; SMN2TSHRMAPTFAAHALDH1A1
SCHEMBL4604213 0.80
SCHEMBL10161479 0.80 TSHR (0.40) SMN1; SMN2TSHRMAPTFAAHALDH1A1
SCHEMBL6687715 0.79 TSHR (1.00) SMN1; SMN2TSHRMAPTFAAHALDH1A1
SCHEMBL14651983 0.77 SMN1; SMN2 (0.71) SMN1; SMN2TSHRMAPTFAAHALDH1A1
SCHEMBL6474695 0.77
SCHEMBL25702503 0.77 TSHR (0.95) SMN1; SMN2TSHRMAPTFAAHALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1102752-A1 SUCCINOYLAMINO LACTAMS AS INHIBITORS OF A BETA PROTEIN PRODUCTION Du Pont Pharmaceuticals Company (US) 2001-05-30 EP claimed
WO-2000007995-A1 SUCCINOYLAMINO LACTAMS AS INHIBITORS OF Aβ PROTEIN PRODUCTION DU PONT PHARMACEUTICALS COMPANY (US) 2000-02-17 WO claimed
EP-0866817-B1 PROCESS FOR PREPARING SELF-RELEASING, COMPACT OR CELLULAR MOULDED BODIES OPTIONALLY CONTAINING REINFORCING AGENTS AND MADE OF POLYISOCYANATE POLYADDITON PRODUCTS AND INTERNAL MOULD RELEASE AGENTS THEREFOR BASF AG (DE) 1999-09-01 EP claimed
EP-0383359-A2 Process for preparing an overbased additive containing a boron derivative, additive produced by said process and lubricating compositions containing said additive ELF ANTAR FRANCE (FR) 1990-08-22 EP claimed
US-4859352-A BLEND OF LITHIUM SOAP, SYNTHETIC OIL, AND ADJUVANTS AMOCO CORPORATION (US) 1989-08-22 US claimed
JP-9078074-A None JP disclosed
CN-113631595-B Polymer composition and use thereof 罗地亚经营管理公司 2023-04-11 CN disclosed
CN-115698128-A Tocopherol-based nonionic and anionic surfactants 巴斯夫欧洲公司 2023-02-03 CN disclosed
CN-114981057-A Method for vulcanizing green tire using organopolysiloxane-based mold release lubricating composition 埃肯有机硅法国简易股份公司 2022-08-30 CN disclosed
CN-110225963-B Polyorganosiloxane-based composition intended for tyre moulding-demoulding 埃肯有机硅法国简易股份公司 2022-01-11 CN disclosed
CN-113874411-A Structure of associative polymers and method of use thereof 罗地亚经营管理公司 2021-12-31 CN disclosed
CN-113631595-A Polymer composition and use thereof 罗地亚经营管理公司 2021-11-09 CN disclosed
JP-H0978074-A LIGHT OIL COMPOSITION NIPPON OIL CO LTD 1997-03-25 JP disclosed
US-5525247-A CONTAINING BORON-CONTAINING DISPERSANT AND DETERGENT IDEMITSU KOSAN CO., LTD. (JP) 1996-06-11 US disclosed
EP-0383359-A2 Process for preparing an overbased additive containing a boron derivative, additive produced by said process and lubricating compositions containing said additive ELF ANTAR FRANCE (FR) 1990-08-22 EP disclosed
EP-0308445-A1 PROCESS FOR THE PREPARATION OF A SUPERALKALINIZED ADDITIVE CONTAINING AN INORGANIC BORON DERIVATIVE, ADDITIVE PRODUCED BY SAID PROCESS AND LUBRICATING COMPOSITIONS CONTAINING SAID ADDITIVE. ELF FRANCE (FR) 1989-03-29 EP disclosed
WO-1988007073-A1 PROCESS FOR THE PREPARATION OF A SUPERALKANIZED ADDITIVE CONTAINING A BORON DERIVATIVE, ADDITIVE PRODUCED BY SAID PROCESS AND LUBRICATING COMPOSITIONS CONTAINING SAID ADDITIVE ELF FRANCE (FR) 1988-09-22 WO disclosed
US-4574058-A Antigen derivatives and processes for their preparation CIBA-GEIGY CORPORATION (US) 1986-03-04 US disclosed
US-4446128-A Antigen derivatives and processes for their preparation CIBA-GEIGY CORPORATION (US) 1984-05-01 US disclosed
US-4397844-A Antigen derivatives and processes for their preparation CIBA-GEIGY CORPORATION (US) 1983-08-09 US disclosed