Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KDM5C | P41229 | 2/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16566001 | 0.89 | MAPT (0.54) | TSHRSMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL12838003 | 0.83 | TSHR (0.42) | TSHRSMN1; SMN2MAPTKDM4EKDM5C | |
| SCHEMBL14397823 | 0.81 | PHF8 (0.50) | TSHRSMN1; SMN2MAPTKDM4EKDM5C | |
| SCHEMBL7375016 | 0.80 | SMN1; SMN2 (0.65) | TSHRSMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL17793319 | 0.79 | — | — | |
| SCHEMBL12838131 | 0.77 | LMNA (0.43) | TSHRSMN1; SMN2MAPTKDM4EKDM5C | |
| SCHEMBL14391566 | 0.77 | ALDH1A1 (0.46) | TSHRSMN1; SMN2MAPTKDM4EKDM5C | |
| SCHEMBL3857659 | 0.77 | TSHR (0.36) | TSHRSMN1; SMN2MAPTFAAH | |
| SCHEMBL11959163 | 0.76 | TSHR (0.48) | TSHRSMN1; SMN2MAPTFAAHTPSAB1 | |
| SCHEMBL871580 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101186-B2 | Peptides that block the binding of IgG to FcRn | SYNTONIX PHARMACEUTICALS, INC. (US) | 2012-01-24 | — | — | US | disclosed |