Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 8/20 | 0.65 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.54 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.54 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371867 | 0.94 | TERT (0.64) | TERTCSNK2A2CSNK2BCSNK2A1TDP1 | |
| SCHEMBL7375563 | 0.90 | TERT (0.52) | TERTCSNK2A2CSNK2BCSNK2A1TDP1 | |
| SCHEMBL7374824 | 0.90 | TERT (0.65) | TERTCSNK2A2CSNK2BCSNK2A1CYP3A4 | |
| SCHEMBL7380070 | 0.90 | HPGD (0.65) | TERTCSNK2A2CSNK2BCSNK2A1TDP1 | |
| SCHEMBL7371005 | 0.88 | CYP1A2 (0.52) | TERTCSNK2A2CSNK2BCSNK2A1CYP1A1 | |
| SCHEMBL7378981 | 0.88 | TERT (0.52) | TERTCSNK2A2CSNK2BCSNK2A1CYP1A2 | |
| SCHEMBL7371816 | 0.86 | CSNK2A2 (0.59) | TERTCSNK2A2CSNK2BCSNK2A1CYP3A4 | |
| SCHEMBL7378867 | 0.86 | CYP3A4 (0.67) | TERTCSNK2A2CSNK2BCSNK2A1CYP1A1 | |
| SCHEMBL7380087 | 0.84 | CSNK2A2 (0.67) | TERTCSNK2A2CSNK2BCSNK2A1CYP3A4 | |
| SCHEMBL7380352 | 0.83 | CSNK2A2 (0.62) | TERTCSNK2A2CSNK2BCSNK2A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115718-A1 | HYDROXYFLAVONE DERIVATIVES AS TAU PROTEIN KINASE 1 INHIBITORS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000017184-A1 | HYDROXYFLAVONE DERIVATIVES AS TAU PROTEIN KINASE 1 INHIBITORS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-03-30 | — | — | WO | disclosed |