Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 8/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375040 | 0.90 | TERT (0.65) | TERTCYP1A1CYP1A2CYP1B1MAOB | |
| SCHEMBL7380070 | 0.88 | HPGD (0.65) | TERTCYP1A1CYP1A2CYP1B1XDH | |
| SCHEMBL7374824 | 0.88 | TERT (0.65) | TERTKDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL7378981 | 0.85 | TERT (0.52) | TERTCYP1A2MAOBKDM4EALDH1A1 | |
| SCHEMBL7371005 | 0.85 | CYP1A2 (0.52) | TERTCYP1A1CYP1A2CYP1B1MAOB | |
| SCHEMBL7371816 | 0.84 | CSNK2A2 (0.59) | TERTMAOBKDM4EALDH1A1TP53 | |
| SCHEMBL7371867 | 0.84 | TERT (0.64) | TERTCYP1A1CYP1A2CYP1B1MAOB | |
| SCHEMBL7380087 | 0.82 | CSNK2A2 (0.67) | TERTKDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL3181663 | 0.82 | PDE5A (0.59) | TERTCYP1A1CYP1A2CYP1B1XDH | |
| SCHEMBL7378867 | 0.82 | CYP3A4 (0.67) | TERTCYP1A1CYP1A2CYP1B1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115718-A1 | HYDROXYFLAVONE DERIVATIVES AS TAU PROTEIN KINASE 1 INHIBITORS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000017184-A1 | HYDROXYFLAVONE DERIVATIVES AS TAU PROTEIN KINASE 1 INHIBITORS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-03-30 | — | — | WO | disclosed |