Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.51 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21753692 | 0.87 | EPHX1 (0.52) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9472003 | 0.84 | MAPK1 (0.47) | MAPK1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7320938 | 0.83 | NPC1 (0.64) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11656121 | 0.81 | ALDH1A1 (0.62) | MAPK1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| Phenyl M-Tolylcarbamate SCHEMBL259420 | 0.80 | ALDH1A1 (0.78) | MAPK1MEN1KMT2ARAB9ASMN1; SMN2 | |
| Phenyl M-Tolylcarbamate SCHEMBL29739712 | 0.80 | ALDH1A1 (0.78) | MAPK1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9156863 | 0.80 | KMT2A (0.57) | MAPK1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL31054278 | 0.77 | SMN1; SMN2 (0.75) | MAPK1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL259602 | 0.77 | SMN1; SMN2 (0.75) | MAPK1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9472191 | 0.77 | KMT2A (0.55) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042656-A1 | NOVEL COMPOUNDS | CYTEL CORPORATION (US) | 1998-10-01 | — | — | WO | disclosed |