Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9471767 | 0.90 | THRB (0.50) | MAPK1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9297101 | 0.88 | PKM (0.51) | MEN1KMT2ANPC1RAB9ATHRB | |
| SCHEMBL9297882 | 0.88 | MAPT (0.46) | MAPK1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9156740 | 0.87 | PKM (0.57) | MEN1KMT2ANPC1RAB9ATHRB | |
| SCHEMBL9157115 | 0.87 | MEN1 (0.50) | MAPK1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9158384 | 0.87 | MAPT (0.46) | MAPK1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9471775 | 0.87 | MAPT (0.49) | MEN1KMT2ANPC1RAB9ATHRB | |
| SCHEMBL9471546 | 0.85 | THRB (0.45) | MAPK1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9471257 | 0.85 | THRB (0.45) | MAPK1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9298028 | 0.85 | MEN1 (0.43) | MAPK1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223529-A | Nervous system and gastrointestinal disorders | RHONE-POULENC SANTE (FR) | 1993-06-29 | — | — | US | disclosed |