Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 9/20 | 0.50 |
| ▸ | GSK3B | P49841 | 7/20 | 0.50 |
| ▸ | KDR | P35968 | 6/20 | 0.50 |
| ▸ | GSK3A | P49840 | 6/20 | 0.50 |
| ▸ | CLK2 | P49760 | 6/20 | 0.50 |
| ▸ | STK17A | Q9UEE5 | 5/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.50 |
| ▸ | HIPK4 | Q8NE63 | 4/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.50 |
| ▸ | STK3 | Q13188 | 3/20 | 0.50 |
| ▸ | PBK | Q96KB5 | 3/20 | 0.50 |
| ▸ | PRKD2 | Q9BZL6 | 3/20 | 0.50 |
| ▸ | CDK2 | P24941 | 3/20 | 0.50 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.50 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.50 |
| ▸ | SGK2 | Q9HBY8 | 3/20 | 0.50 |
| ▸ | MAP3K20 | Q9NYL2 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7656149 | 0.99 | CLK4 (0.49) | CLK4GSK3BKDRGSK3ACLK2 | |
| Hydrochloric Acid SCHEMBL7659942 | 0.82 | HTR2C (0.54) | CLK4GSK3BKDRGSK3ACLK2 | |
| Hydrochloric Acid SCHEMBL7653204 | 0.79 | HTR2C (0.54) | CLK4GSK3BKDRGSK3ACLK2 | |
| SCHEMBL27579461 | 0.78 | PLK4 (0.73) | CLK4GSK3BKDRGSK3ACLK2 | |
| SCHEMBL10965342 | 0.77 | MAPT (0.48) | KDR | |
| Hydrochloric Acid SCHEMBL7659429 | 0.75 | CLK4 (0.50) | CLK4GSK3BKDRGSK3ACLK2 | |
| SCHEMBL10008185 | 0.72 | CLK4 (0.78) | CLK4GSK3BKDRGSK3ACLK2 | |
| SCHEMBL3807061 | 0.72 | HTR2C (0.73) | CLK4GSK3BKDRGSK3ACLK2 | |
| SCHEMBL7654391 | 0.72 | HTR2C (0.67) | GSK3BKDRGSK3AHTR2CHTR2B | |
| SCHEMBL3795773 | 0.71 | CLK4 (0.74) | CLK4GSK3BKDRGSK3ACLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003737-A1 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS HFGAN72 ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999009024-A1 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS HFGAN72 ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1999-02-25 | — | — | WO | disclosed |