Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28600366 | 0.79 | RXFP1 (0.43) | MAPTGPR35CA1CA2 | |
| SCHEMBL7375370 | 0.77 | CLK4 (0.50) | KDR | |
| SCHEMBL22103786 | 0.75 | EPHX2 (0.61) | MAPTTP53GAAEPHX2MEN1 | |
| SCHEMBL11551983 | 0.70 | CYP3A4 (0.36) | MAPTTP53GAARAB9AGPR35 | |
| SCHEMBL10465570 | 0.69 | LMNA (0.32) | GAAMEN1KMT2AHTT | |
| SCHEMBL25552244 | 0.68 | DAO (0.50) | MEN1KMT2AGPR35ALDH1A1CES2 | |
| SCHEMBL2681462 | 0.67 | MAPT (0.78) | MAPTEPHX2MEN1KMT2ARAB9A | |
| SCHEMBL10465569 | 0.67 | HPGD (0.33) | MEN1KMT2AHTT | |
| SCHEMBL18691870 | 0.67 | MAPT (0.50) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL27397192 | 0.64 | RXRA (0.44) | ALDH1A1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058424-B1 | PYRAZOLINE DERIVATIVES | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1985-09-18 | — | — | EP | disclosed |
| US-4464386-A | Insecticidal 3-difluoromethoxyphenyl-1-phenylcarbamoyl-2-pyrazolines | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1984-08-07 | — | — | US | disclosed |
| EP-0058424-A2 | Pyrazoline derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1982-08-25 | — | — | EP | disclosed |