Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.64 |
| ▸ | CTSS | P25774 | 6/20 | 0.64 |
| ▸ | CTSL | P07711 | 6/20 | 0.64 |
| ▸ | CTSB | P07858 | 3/20 | 0.64 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27570775 | 0.87 | CTSK (0.66) | CTSKCTSSCTSLCTSBPSMB1 | |
| SCHEMBL27494131 | 0.84 | CTSK (0.56) | CTSKCTSSCTSLCTSB | |
| SCHEMBL724023 | 0.82 | CTSK (0.44) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7606122 | 0.81 | CTSB (0.43) | CTSKCTSSCTSLCTSB | |
| SCHEMBL14611591 | 0.79 | CTSK (0.74) | CTSKCTSSCTSLCTSB | |
| SCHEMBL5934705 | 0.79 | CTSK (0.58) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7639995 | 0.79 | CTSK (0.43) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7181854 | 0.78 | CTSK (0.70) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6183072 | 0.78 | CTSK (0.80) | CTSKCTSSCTSLCTSB | |
| SCHEMBL608854 | 0.78 | CTSK (0.72) | CTSKCTSSCTSLCTSBPSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934291-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0934291-A4 | — | SMITHKLINE BEECHAM CORP (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1997016433-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-09 | — | — | WO | disclosed |