Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 18/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635663 | 0.92 | CCKBR (1.00) | CCKBR | |
| SCHEMBL8635695 | 0.91 | CCKBR (1.00) | CCKBR | |
| SCHEMBL8636478 | 0.91 | CCKBR (1.00) | CCKBR | |
| SCHEMBL8659328 | 0.91 | CCKBR (1.00) | CCKBR | |
| SCHEMBL8656811 | 0.91 | CCKBR (1.00) | CCKBR | |
| SCHEMBL8656788 | 0.90 | CCKBR (0.82) | CCKBR | |
| SCHEMBL8867367 | 0.89 | CCKBR (0.88) | CCKBR | |
| SCHEMBL1388061 | 0.89 | CCKBR (0.88) | CCKBR | |
| SCHEMBL8638672 | 0.89 | CCKBR (0.81) | CCKBR | |
| SCHEMBL8635744 | 0.89 | CCKBR (1.00) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413930-B1 | CONTROLLING EYE MOVEMENT | GLAXO WELLCOME SPA (IT) | 2002-07-02 | — | — | US | claimed |
| EP-0785788-B1 | USE OF CCK-B RECEPTOR ANTAGONISTS FOR THE TREATMENT OF SLEEP DISORDERS | GLAXO WELLCOME SPA (IT) | 2001-12-12 | — | — | EP | claimed |
| EP-0828479-B1 | METHOD OF PRODUCING A SOLID DISPERSION OF A POORLY WATER SOLUBLE DRUG | ICOS CORP (US) | 2001-10-24 | — | — | EP | claimed |
| US-5985326-A | MIXING WITH SOLVENT; COPRECIPITATION; 2,3,6,7,12,12A-HEXAHYDRO-2-METHYL-6-(3,4-METHYLENEDIOXYPHENYL) -PYRAZINO(2',1':6,1)PYRIDO(3,4-B)INDOLE-1,4-DIONE | ICOS CORPORATION (US) | 1999-11-16 | — | — | US | claimed |
| EP-0558104-B1 | 1,5-Benzodiazepine derivatives and their use in medicine | GLAXO WELLCOME SPA (IT) | 1998-07-29 | — | — | EP | claimed |
| EP-0828479-A1 | METHOD OF PRODUCING A SOLID DISPERSION OF A POORLY WATER SOLUBLE DRUG | GLAXO GROUP LIMITED (GB) | 1998-03-18 | — | — | EP | claimed |
| EP-0785788-A1 | USE OF CCK-B RECEPTOR ANTAGONISTS FOR THE TREATMENT OF SLEEP DISORDERS | GLAXO WELLCOME S.p.A. (IT) | 1997-07-30 | — | — | EP | claimed |
| WO-1996038131-A1 | METHOD OF PRODUCING A SOLID DISPERSION OF A POORLY WATER SOLUBLE DRUG | GLAXO GROUP LIMITED (GB) | 1996-12-05 | — | — | WO | claimed |
| WO-1996011689-A1 | USE OF CCK-B RECEPTOR ANTAGONISTS FOR THE TREATMENT OF SLEEP DISORDERS | GLAXO WELLCOME SPA (IT) | 1996-04-25 | — | — | WO | claimed |
| EP-0558104-A1 | 1,5-Benzodiazepine derivatives and their use in medicine | GLAXO S.p.A. (IT) | 1993-09-01 | — | — | EP | claimed |
| WO-1993014074-A1 | 1,5-BENZODIAZEPINE DERIVATIVES AND THEIR USE IN MEDICINE | GLAXO SPA (IT) | 1993-07-22 | — | — | WO | claimed |
| JP-7118244-A | — | — | None | — | — | JP | disclosed |
| US-6413930-B1 | CONTROLLING EYE MOVEMENT | GLAXO WELLCOME SPA (IT) | 2002-07-02 | — | — | US | disclosed |
| EP-0785788-B1 | USE OF CCK-B RECEPTOR ANTAGONISTS FOR THE TREATMENT OF SLEEP DISORDERS | GLAXO WELLCOME SPA (IT) | 2001-12-12 | — | — | EP | disclosed |
| EP-0828479-B1 | METHOD OF PRODUCING A SOLID DISPERSION OF A POORLY WATER SOLUBLE DRUG | ICOS CORP (US) | 2001-10-24 | — | — | EP | disclosed |
| US-5580895-A | GASTROINTESTINAL OR CENTRAL NERVOUS SYSTEM DISORDERS | GLAXO SPA (IT) | 1996-12-03 | — | — | US | disclosed |
| WO-1996011689-A1 | USE OF CCK-B RECEPTOR ANTAGONISTS FOR THE TREATMENT OF SLEEP DISORDERS | GLAXO WELLCOME SPA (IT) | 1996-04-25 | — | — | WO | disclosed |
| JP-H07118244-A | 1,5-BENZODIAZEPINE DERIVATIVE | GLAXO SPA | 1995-05-09 | — | — | JP | disclosed |
| EP-0558104-A1 | 1,5-Benzodiazepine derivatives and their use in medicine | GLAXO S.p.A. (IT) | 1993-09-01 | — | — | EP | disclosed |
| WO-1993014074-A1 | 1,5-BENZODIAZEPINE DERIVATIVES AND THEIR USE IN MEDICINE | GLAXO SPA (IT) | 1993-07-22 | — | — | WO | disclosed |