SCHEMBL8867367

SCHEMBL8867367

CN1C(=O)C(NC(=O)Nc2ccccc2)C(=O)N(CC23CC4CC(CC(C4)C2)C3)c2ccccc21

nearest known ligand 0.88

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 15/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1388061 0.90 CCKBR (0.88) CCKBR
SCHEMBL7375453 0.89 CCKBR (1.00) CCKBR
SCHEMBL8866497 0.89 CCKBR (1.00) CCKBR
SCHEMBL7736909 0.89 CCKBR (0.81) CCKBR
SCHEMBL1388262 0.88 CCKBR (0.85) CCKBR
SCHEMBL8556662 0.87 CCKBR (0.79) CCKBR
SCHEMBL1388127 0.85 CCKBR (0.76) CCKBR
SCHEMBL7926069 0.85 CCKBR (0.79) CCKBR
SCHEMBL1387839 0.85 CCKBR (1.00) CCKBR
SCHEMBL8665956 0.84 CCKBR (0.80) CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5686449-A 1,5-benzodiazepines useful as gastrinor CCK-antagonists GLAXO WELLCOME S.P.A. (IT) 1997-11-11 US disclosed