Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8682517 | 0.91 | KMT2A (0.53) | KMT2APOLBMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7372988 | 0.90 | KMT2A (0.52) | KMT2APOLBMEN1SMN1; SMN2CCR1 | |
| SCHEMBL8687594 | 0.89 | KMT2A (0.51) | KMT2APOLBMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8684514 | 0.89 | KMT2A (0.51) | KMT2APOLBMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8682520 | 0.87 | KMT2A (0.49) | KMT2APOLBMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7368133 | 0.84 | KMT2A (0.64) | KMT2APOLBL3MBTL1SMN1; SMN2GAA | |
| SCHEMBL9828182 | 0.82 | KMT2A (0.79) | KMT2APOLBMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9828111 | 0.81 | KMT2A (0.68) | KMT2APOLBL3MBTL1SMN1; SMN2GAA | |
| SCHEMBL8488336 | 0.80 | POLB (0.56) | KMT2APOLBSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL9828399 | 0.80 | KMT2A (0.66) | KMT2APOLBMEN1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929074-A | VSODILATOR, ANTIALLERGIC AND ANTIPLATELET AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| EP-0706517-B1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL IND LTD (JP) | 1998-10-21 | — | — | EP | disclosed |
| US-5728702-A | BRONCHODILATOR AGENTS, ANTIALLERGENS OR ANTIPLATELET DRUGGS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0706517-A1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001343-A1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1995-01-12 | — | — | WO | disclosed |