Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.79 |
| ▸ | POLB | P06746 | 2/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828111 | 0.92 | KMT2A (0.68) | KMT2APOLBSMN1; SMN2GAAPKM | |
| SCHEMBL9828399 | 0.90 | KMT2A (0.66) | KMT2APOLBSMN1; SMN2GAAPKM | |
| SCHEMBL7368133 | 0.89 | KMT2A (0.64) | KMT2APOLBSMN1; SMN2GAAPKM | |
| SCHEMBL9828492 | 0.89 | KMT2A (0.64) | KMT2APOLBSMN1; SMN2GAAPKM | |
| SCHEMBL9827887 | 0.88 | KMT2A (0.63) | KMT2APOLBSMN1; SMN2PKMLMNA | |
| SCHEMBL27890025 | 0.88 | POLB (1.00) | KMT2APOLBSMN1; SMN2GAAPKM | |
| SCHEMBL9827437 | 0.88 | POLB (0.62) | KMT2APOLBSMN1; SMN2LMNAMAPT | |
| SCHEMBL9829304 | 0.85 | KMT2A (0.58) | KMT2APOLBSMN1; SMN2GAALMNA | |
| SCHEMBL8488336 | 0.83 | POLB (0.56) | KMT2APOLBSMN1; SMN2LMNAMAPT | |
| SCHEMBL7375489 | 0.82 | KMT2A (0.55) | KMT2APOLBSMN1; SMN2GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201765-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1991-09-18 | — | — | EP | claimed |
| US-4892947-A | 3(2H)Pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-01-09 | — | — | US | claimed |
| EP-0201765-A2 | 3(2H)Pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-11-20 | — | — | EP | claimed |