Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.38 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367149 | 0.91 | POLB (0.54) | POLBKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL8485725 | 0.90 | KMT2A (0.53) | POLBKMT2ASMN1; SMN2HTR1ADRD2 | |
| SCHEMBL9828492 | 0.87 | KMT2A (0.64) | POLBKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL9827887 | 0.86 | KMT2A (0.63) | POLBKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL9828399 | 0.86 | KMT2A (0.66) | POLBKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL7374617 | 0.85 | KMT2A (0.54) | POLBKMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9827437 | 0.85 | POLB (0.62) | POLBKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL9828111 | 0.84 | KMT2A (0.68) | POLBKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL9828182 | 0.83 | KMT2A (0.79) | POLBKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL7375489 | 0.80 | KMT2A (0.55) | POLBKMT2ALMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929074-A | VSODILATOR, ANTIALLERGIC AND ANTIPLATELET AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| EP-0706517-B1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL IND LTD (JP) | 1998-10-21 | — | — | EP | disclosed |