Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | FADS1 | O60427 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 3/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7380716 | 0.99 | KDR (0.51) | KDRNPC1RAB9AGRM4HDAC6 | |
| Hydrochloric Acid SCHEMBL7444958 | 0.84 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7448873 | 0.84 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL16007711 | 0.84 | KDR (0.57) | KDRNPC1RAB9AGRM4HDAC6 | |
| SCHEMBL17399519 | 0.78 | KDR (0.51) | KDRNPC1RAB9AGRM4HDAC6 | |
| SCHEMBL16007162 | 0.77 | KDR (0.53) | KDRNPC1RAB9AGRM4HDAC6 | |
| SCHEMBL16007161 | 0.77 | KDR (0.53) | KDRNPC1RAB9AGRM4HDAC6 | |
| SCHEMBL16007332 | 0.77 | KDR (0.53) | KDRNPC1RAB9AGRM4HDAC6 | |
| SCHEMBL7381197 | 0.76 | KCNMA1 (0.52) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL16007186 | 0.75 | KDR (0.54) | KDRNPC1RAB9AGRM4HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140881-A1 | ANTITHROMBOTIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039111-A1 | ANTITHROMBOTIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |