Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358439 | 0.86 | F10 (0.51) | KDM4EF10ALDH1A1NPC1RAB9A | |
| SCHEMBL7372750 | 0.85 | KCNMA1 (0.46) | KCNMA1KDM4EGAAHPGDALOX15 | |
| SCHEMBL6714678 | 0.83 | NPC1 (0.53) | ALOX15F10SMN1; SMN2TDP1NPC1 | |
| Hydrochloric Acid SCHEMBL7358233 | 0.80 | F10 (0.49) | F10 | |
| SCHEMBL5758058 | 0.80 | KCNMA1 (0.55) | KCNMA1KDM4EGAAHPGDALOX15 | |
| SCHEMBL7356229 | 0.79 | F10 (0.48) | F10MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7444958 | 0.78 | NPC1 (0.46) | ALOX15F10SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7448873 | 0.78 | NPC1 (0.46) | ALOX15F10SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7446146 | 0.77 | F10 (0.49) | ALOX15F10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7365101 | 0.77 | F10 (0.46) | ALOX15F10SMN1; SMN2TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140881-A1 | ANTITHROMBOTIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039111-A1 | ANTITHROMBOTIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |