Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 2/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375605 | 1.00 | CNR2 (0.49) | CNR2TSHRKEAP1ANPEPERAP1 | |
| SCHEMBL1857365 | 0.83 | CYP1A2 (0.61) | KEAP1ANPEPERAP1ERAP2CYP1A2 | |
| Water SCHEMBL4010621 | 0.81 | CYP1A2 (0.59) | CNR2ANPEPERAP1ERAP2CYP1A2 | |
| SCHEMBL2291948 | 0.80 | MMP8 (0.56) | CNR2TSHRKEAP1ANPEPERAP1 | |
| SCHEMBL360781 | 0.77 | CNR2 (0.50) | CNR2TSHRKEAP1ANPEPERAP1 | |
| SCHEMBL7439193 | 0.77 | GRIK1 (0.64) | ANPEPERAP1ERAP2CYP1A2 | |
| SCHEMBL7439191 | 0.77 | GRIK1 (0.64) | ANPEPERAP1ERAP2CYP1A2 | |
| SCHEMBL233440 | 0.77 | CNR2 (0.50) | CNR2TSHRKEAP1ANPEPERAP1 | |
| SCHEMBL233441 | 0.77 | CNR2 (0.50) | CNR2TSHRKEAP1ANPEPERAP1 | |
| SCHEMBL7439419 | 0.77 | GRIK1 (0.64) | ANPEPERAP1ERAP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929542-A1 | COMPOUNDS FOR AND A METHOD OF INHIBITING MATRIX METALLOPROTEINASES | WARNER-LAMBERT COMPANY (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998009957-A1 | COMPOUNDS FOR AND A METHOD OF INHIBITING MATRIX METALLOPROTEINASES | WARNER-LAMBERT COMPANY (US) | 1998-03-12 | — | — | WO | disclosed |