Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MTTP | P55157 | 8/20 | 0.40 |
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372417 | 0.90 | ALDH1A1 (0.47) | KMT2AMEN1KDM4EALDH1A1POLB | |
| SCHEMBL7368867 | 0.89 | KDM4E (0.43) | KMT2AMEN1KDM4ERXFP1MTTP | |
| SCHEMBL7374862 | 0.87 | ALDH1A1 (0.46) | KMT2AMEN1KDM4EALDH1A1POLB | |
| SCHEMBL7374130 | 0.86 | ALDH1A1 (0.45) | HTTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7372810 | 0.86 | ALDH1A1 (0.44) | HTTKMT2AMEN1KDM4EMTTP | |
| SCHEMBL7376228 | 0.85 | ALDH1A1 (0.51) | HTTKMT2AMEN1KDM4EMTTP | |
| SCHEMBL7374746 | 0.85 | KMT2A (0.47) | HTTKMT2AMEN1KDM4ERXFP1 | |
| SCHEMBL7748371 | 0.84 | F10 (0.38) | KDM4ERXFP1MTTPF10ALDH1A1 | |
| SCHEMBL7373196 | 0.83 | MTTP (0.40) | KMT2AMEN1KDM4ERXFP1MTTP | |
| SCHEMBL7375888 | 0.82 | POLB (0.44) | HTTKDM4EMTTPALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |