Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.38 |
| ▸ | MTTP | P55157 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375729 | 0.91 | AVPR2 (0.41) | KDM4EAVPR2AVPR1AAVPR1BALDH1A1 | |
| SCHEMBL7367751 | 0.89 | AVPR2 (0.40) | KDM4EAVPR2AVPR1AAVPR1BALDH1A1 | |
| SCHEMBL7374551 | 0.88 | AVPR2 (0.40) | KDM4EAVPR2AVPR1AAVPR1BALDH1A1 | |
| SCHEMBL7371827 | 0.88 | AVPR2 (0.42) | MTTPAVPR2AVPR1AAVPR1BALDH1A1 | |
| SCHEMBL7374590 | 0.86 | AVPR2 (0.44) | MTTPAVPR2AVPR1AAVPR1B | |
| SCHEMBL7373631 | 0.86 | NAMPT (0.43) | F10KDM4EAVPR2AVPR1AAVPR1B | |
| SCHEMBL7373196 | 0.84 | MTTP (0.40) | F10MTTPKDM4ERXFP1ALDH1A1 | |
| SCHEMBL7376078 | 0.84 | AVPR2 (0.42) | MTTPKDM4EAVPR2AVPR1AAVPR1B | |
| SCHEMBL7375706 | 0.84 | HTT (0.46) | F10MTTPKDM4ERXFP1ALDH1A1 | |
| SCHEMBL7368867 | 0.84 | KDM4E (0.43) | F10MTTPKDM4ERXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |