Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 7/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16298724 | 0.87 | EPHX1 (0.46) | EPHX1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13519757 | 0.87 | EPHX1 (0.46) | EPHX1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8591965 | 0.86 | ALDH1A1 (0.38) | EPHX1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23541601 | 0.82 | EPHX1 (0.53) | EPHX1ACHEPLA2G2APLA2G5NAAA | |
| SCHEMBL12705745 | 0.81 | EPHX1 (0.56) | EPHX1ACHEPLA2G2APLA2G5NAAA | |
| SCHEMBL12705744 | 0.81 | EPHX1 (0.56) | EPHX1ACHEPLA2G2APLA2G5NAAA | |
| SCHEMBL18248174 | 0.81 | POLB (0.36) | EPHX1ALDH1A1HPGDL3MBTL1ATM | |
| SCHEMBL7389962 | 0.80 | ALDH1A1 (0.44) | EPHX1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26361145 | 0.80 | EPHX1 (0.40) | EPHX1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2448759 | 0.78 | EPHX1 (0.45) | EPHX1ALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934291-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0934291-A4 | — | SMITHKLINE BEECHAM CORP (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1997016433-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-09 | — | — | WO | disclosed |