Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.58 |
| ▸ | CTSB | P07858 | 4/20 | 0.58 |
| ▸ | CTSK | P43235 | 10/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 3/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6578032 | 0.90 | CTSL (0.60) | CTSLCTSBCTSKCYP3A4CTSS | |
| SCHEMBL27497095 | 0.90 | CTSL (0.60) | CTSLCTSBCTSKCYP3A4CTSS | |
| Lithium SCHEMBL7162098 | 0.89 | CTSL (0.59) | CTSLCTSBCTSKCYP3A4CTSS | |
| SCHEMBL7162081 | 0.89 | CTSL (0.59) | CTSLCTSBCTSKCYP3A4CTSS | |
| Lithium Ion SCHEMBL7162088 | 0.88 | CTSL (0.56) | CTSLCTSBCTSKCYP3A4CTSS | |
| SCHEMBL27563904 | 0.85 | CTSK (0.56) | CTSLCTSBCTSKCTSSCAPN1 | |
| SCHEMBL7159540 | 0.85 | CTSK (0.56) | CTSLCTSBCTSKCTSSCAPN1 | |
| SCHEMBL14609392 | 0.84 | CTSK (0.74) | CTSLCTSBCTSKCTSSCAPN1 | |
| SCHEMBL13611959 | 0.84 | CTSK (0.74) | CTSLCTSBCTSKCTSSCAPN1 | |
| SCHEMBL3978105 | 0.84 | CTSK (0.74) | CTSLCTSBCTSKCTSSCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934291-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0934291-A4 | — | SMITHKLINE BEECHAM CORP (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1997016433-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-09 | — | — | WO | disclosed |