Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MTTP | P55157 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | MELK | Q14680 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373482 | 0.92 | ALDH1A1 (0.44) | ALDH1A1MTTPGAAMAPTNPC1 | |
| SCHEMBL8812151 | 0.91 | GAA (0.41) | ALDH1A1MTTPGAAMAPTCTDSP1 | |
| SCHEMBL7368067 | 0.89 | RECQL (0.45) | ALDH1A1GAAMAPTRAB9AAVPR2 | |
| SCHEMBL7372810 | 0.89 | ALDH1A1 (0.44) | ALDH1A1MTTPMAPTNPC1RAB9A | |
| SCHEMBL7378355 | 0.86 | RECQL (0.44) | ALDH1A1GAAMAPTRAB9AAVPR2 | |
| SCHEMBL7375925 | 0.86 | MTTP (0.40) | ALDH1A1MTTPGAAMAPTCTDSP1 | |
| SCHEMBL7377742 | 0.85 | RECQL (0.43) | ALDH1A1GAAMAPTAVPR2AVPR1A | |
| SCHEMBL7368867 | 0.85 | KDM4E (0.43) | ALDH1A1MTTPGAAMAPTNPC1 | |
| SCHEMBL7368434 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MTTPGAAMAPTL3MBTL1 | |
| SCHEMBL7371827 | 0.84 | AVPR2 (0.42) | ALDH1A1MTTPGAAAVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |