Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MTTP | P55157 | 5/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378000 | 0.89 | ALDH1A1 (0.51) | ALDH1A1GAAMTTPMAPTLMNA | |
| SCHEMBL7376741 | 0.87 | CHRNB2 (0.49) | ALDH1A1GAAHSD17B1HSD17B2LMNA | |
| SCHEMBL7373393 | 0.86 | ALDH1A1 (0.47) | ALDH1A1GAAMTTPMAPTF10 | |
| SCHEMBL7376100 | 0.84 | ALDH1A1 (0.43) | ALDH1A1GAAMTTPMAPTL3MBTL1 | |
| SCHEMBL7376852 | 0.82 | F10 (0.48) | ALDH1A1GAAMTTPHSD17B1HSD17B2 | |
| SCHEMBL7748399 | 0.81 | ALDH1A1 (0.51) | ALDH1A1GAAMTTPMAPTLMNA | |
| SCHEMBL7372810 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MTTPMAPTL3MBTL1 | |
| SCHEMBL7376652 | 0.79 | PTGER1 (0.46) | ALDH1A1MTTPMAPTL3MBTL1F10 | |
| SCHEMBL7375925 | 0.79 | MTTP (0.40) | ALDH1A1GAAMTTPMAPT | |
| SCHEMBL7513968 | 0.79 | RAB9A (0.46) | ALDH1A1GAAMAPTLMNAF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |