Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2875576 | 0.81 | MAPT (0.45) | PKMMAPTNPC1RAB9AKMT2A | |
| SCHEMBL7375853 | 0.80 | MEN1 (0.48) | SLC6A2SLC6A4MAPTRAB9AKMT2A | |
| Ammonia Solution, Strong SCHEMBL7446734 | 0.78 | AKT1 (0.43) | MAPTNPC1RAB9AKMT2ASMYD3 | |
| SCHEMBL12124647 | 0.74 | MAPT (0.45) | PKMMAPTNPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL15204558 | 0.73 | MAPT (0.44) | PKMMAPTNPC1RAB9AKMT2A | |
| SCHEMBL5756624 | 0.72 | KDR (0.54) | MAPTNPC1RAB9AKMT2AAKT1 | |
| SCHEMBL5760425 | 0.71 | KDR (0.39) | SLC6A2SLC6A4KMT2ACDK2AKT1 | |
| Hydrochloric Acid SCHEMBL7558014 | 0.70 | AKT1 (0.42) | SMYD3CDK2AKT1 | |
| SCHEMBL5760397 | 0.70 | MEN1 (0.56) | PKMMAPTNPC1RAB9AKMT2A | |
| SCHEMBL7451045 | 0.70 | KDR (0.43) | CDK2AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140881-A1 | ANTITHROMBOTIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039111-A1 | ANTITHROMBOTIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |