Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376401 | 0.80 | PKM (0.39) | MEN1KMT2AALDH1A1HTTRAB9A | |
| SCHEMBL14521403 | 0.76 | MEN1 (0.75) | MEN1KMT2AALDH1A1HTTRAB9A | |
| SCHEMBL6410234 | 0.73 | SLC6A3 (0.40) | KMT2AALDH1A1HTTRAB9AAKT1 | |
| SCHEMBL23852951 | 0.70 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1HTTRAB9A | |
| SCHEMBL7256983 | 0.69 | AKT1 (0.48) | MEN1KMT2ARAB9AAKT1CDK2 | |
| SCHEMBL13834721 | 0.69 | MEN1 (0.50) | MEN1KMT2AALDH1A1HTTRAB9A | |
| SCHEMBL29539267 | 0.69 | MEN1 (0.86) | MEN1KMT2AALDH1A1HTTRAB9A | |
| SCHEMBL929466 | 0.69 | MEN1 (0.86) | MEN1KMT2AALDH1A1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL13834520 | 0.68 | MEN1 (0.49) | MEN1KMT2AALDH1A1HTTRAB9A | |
| SCHEMBL31302447 | 0.68 | MEN1 (0.70) | MEN1KMT2AALDH1A1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140881-A1 | ANTITHROMBOTIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039111-A1 | ANTITHROMBOTIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |