Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.45 |
| ▸ | F2 | P00734 | 8/20 | 0.34 |
| ▸ | PLAU | P00749 | 4/20 | 0.34 |
| ▸ | PLG | P00747 | 3/20 | 0.34 |
| ▸ | PLAT | P00750 | 3/20 | 0.34 |
| ▸ | F10 | P00742 | 3/20 | 0.34 |
| ▸ | KLK8 | O60259 | 2/20 | 0.34 |
| ▸ | KLK4 | Q9Y5K2 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | KLK1 | P06870 | 1/20 | 0.31 |
| ▸ | KLK2 | P20151 | 1/20 | 0.31 |
| ▸ | MASP2 | O00187 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | F7 | P08709 | 1/20 | 0.30 |
| ▸ | F3 | P13726 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8125406 | 0.73 | ITGB3 (0.30) | ITGB3ITGA2B | |
| SCHEMBL7844777 | 0.71 | ITGB3 (0.45) | ITGB3ITGA2B | |
| SCHEMBL6989337 | 0.71 | ITGB3 (0.45) | ITGB3ITGA2B | |
| SCHEMBL7790925 | 0.69 | ITGB3 (0.39) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7372378 | 0.69 | ITGB3 (0.39) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL6992922 | 0.69 | ITGB3 (0.43) | ITGB3ITGA2B | |
| SCHEMBL7438736 | 0.68 | ITGB3 (0.53) | ITGB3ITGA2B | |
| SCHEMBL7367239 | 0.68 | ITGB3 (0.39) | ITGB3ITGA2B | |
| SCHEMBL7378464 | 0.68 | MASP2 (0.34) | ITGB3ITGA2BKDM1ARCOR1MASP2 | |
| Hydrochloric Acid SCHEMBL7451925 | 0.67 | ITGB3 (0.52) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-B1 | ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | DU PONT PHARM CO (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1995014683-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-06-01 | — | — | WO | disclosed |