Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.48 |
| ▸ | FNTB | P49356 | 2/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | CTSC | P53634 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726975 | 0.90 | CTSK (0.40) | FNTAFNTBPGGT1BCYP2C19CTSK | |
| SCHEMBL7378502 | 0.84 | HDAC3 (0.53) | MMEHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL8910216 | 0.82 | CYP2C19 (0.54) | FNTAFNTBPGGT1BCYP2C19CTSK | |
| SCHEMBL9444929 | 0.82 | CYP2C19 (0.54) | FNTAFNTBPGGT1BCYP2C19CTSK | |
| SCHEMBL7372917 | 0.82 | CYP2C19 (0.54) | FNTAFNTBPGGT1BCYP2C19CTSK | |
| SCHEMBL7371297 | 0.78 | HRH4 (0.50) | CTSKCTSSMMEHDAC3HDAC4 | |
| SCHEMBL6443866 | 0.78 | MME (0.55) | MME | |
| SCHEMBL6443858 | 0.78 | MME (0.55) | MME | |
| SCHEMBL5870216 | 0.73 | CYP2C19 (0.55) | CYP2C19CTSKCTSSBACE1MME | |
| SCHEMBL10438877 | 0.71 | CTSK (0.38) | CYP2C19CTSKCTSSHSPA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371467-A2 | Beta-amino boron acid derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-06 | — | — | EP | disclosed |
| EP-0354522-A1 | Use of alpha-aminoboronic acid derivatives in prevention and treatement of viral diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-14 | — | — | EP | disclosed |
| EP-0315574-A2 | Renin inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-10 | — | — | EP | disclosed |