Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.39 |
| ▸ | FNTB | P49356 | 2/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376950 | 0.90 | FNTA (0.48) | CTSKCTSSFNTAFNTBPGGT1B | |
| SCHEMBL10438877 | 0.82 | CTSK (0.38) | CTSKCTSSBIRC2CTSLHSPA5 | |
| SCHEMBL8910216 | 0.75 | CYP2C19 (0.54) | CTSKCTSSFNTAFNTBPGGT1B | |
| SCHEMBL9444929 | 0.75 | CYP2C19 (0.54) | CTSKCTSSFNTAFNTBPGGT1B | |
| SCHEMBL7372917 | 0.75 | CYP2C19 (0.54) | CTSKCTSSFNTAFNTBPGGT1B | |
| SCHEMBL7378502 | 0.73 | HDAC3 (0.53) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL7371297 | 0.69 | HRH4 (0.50) | CTSKCTSSHDAC3HDAC4HDAC1 | |
| SCHEMBL14164208 | 0.68 | CTSK (0.68) | CTSKCTSSCTSLCTSCRAB9A | |
| SCHEMBL6661586 | 0.68 | RAB9A (0.50) | CTSKCTSSCTSCRAB9AHDAC1 | |
| SCHEMBL6661590 | 0.68 | RAB9A (0.50) | CTSKCTSSCTSCRAB9AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169841-A | Enzyme inhibitors, hypotensive agents, high enteral bioauailability | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-08 | — | — | US | disclosed |