Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384045 | 0.95 | OPRM1 (0.46) | CHRNB4CHRNA3OPRM1OPRK1OPRL1 | |
| SCHEMBL21179718 | 0.82 | OPRM1 (0.53) | OPRM1OPRK1OPRL1CDC25A | |
| SCHEMBL20229840 | 0.80 | OPRM1 (0.71) | OPRM1OPRK1OPRL1 | |
| SCHEMBL15848582 | 0.79 | OPRM1 (0.46) | OPRM1OPRK1OPRL1CDC25A | |
| SCHEMBL20213174 | 0.78 | OPRM1 (0.54) | OPRM1OPRK1OPRL1 | |
| SCHEMBL23034899 | 0.77 | OPRM1 (0.53) | OPRM1OPRK1OPRL1 | |
| SCHEMBL20212790 | 0.75 | OPRM1 (0.76) | OPRM1OPRK1OPRL1 | |
| SCHEMBL20229838 | 0.75 | OPRM1 (0.76) | OPRM1OPRK1OPRL1 | |
| SCHEMBL15848300 | 0.73 | GPR119 (0.47) | OPRM1OPRK1OPRL1 | |
| SCHEMBL20212793 | 0.73 | OPRM1 (0.56) | OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192770-A | Antiemetic, anxiolytic, cognition activator | SYNTEX (U.S.A.) INC. (US) | 1993-03-09 | — | — | US | disclosed |
| EP-0490263-A1 | Alpha-oxoacetamide derivatives | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |