Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4861474 | 0.77 | GRM5 (0.53) | GRM5CYP1A2 | |
| SCHEMBL7387519 | 0.77 | GRM5 (0.53) | GRM5CYP1A2 | |
| SCHEMBL7422386 | 0.74 | GRM5 (0.60) | GRM5CYP1A2 | |
| SCHEMBL4865123 | 0.74 | GRM5 (0.60) | GRM5CYP1A2 | |
| SCHEMBL4866089 | 0.74 | GRM5 (0.60) | GRM5CYP1A2 | |
| SCHEMBL7419198 | 0.73 | GRM5 (0.59) | GRM5CYP1A2 | |
| SCHEMBL352291 | 0.69 | GRM5 (0.65) | GRM5CYP1A2 | |
| SCHEMBL4860856 | 0.69 | GRM5 (0.64) | GRM5CYP1A2 | |
| SCHEMBL7377481 | 0.68 | GRM5 (0.50) | GRM5CYP1A2 | |
| SCHEMBL4807933 | 0.67 | GRM5 (0.96) | GRM5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214303-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | Merck & Co., Inc. (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001016121-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | MERCK & CO., INC. (US) | 2001-03-08 | — | — | WO | disclosed |