Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7377537 | 0.81 | SLC1A3 (0.37) | CTSKMEN1KMT2ALMNA | |
| SCHEMBL10908162 | 0.79 | ANPEP (0.45) | CTSKCTSSCTSLCTSBALDH1A1 | |
| SCHEMBL11660914 | 0.73 | CTSK (0.43) | CTSKCTSSCTSLCTSBALDH1A1 | |
| SCHEMBL724546 | 0.72 | CTSK (0.46) | CTSKCTSSCTSLCTSB | |
| SCHEMBL27799677 | 0.71 | ANPEP (0.45) | CTSKCTSSCTSLCTSBMEN1 | |
| SCHEMBL27473269 | 0.71 | ANPEP (0.45) | CTSKCTSSCTSLCTSBALDH1A1 | |
| SCHEMBL7615037 | 0.71 | CTSK (0.37) | CTSKCTSSCTSLCTSBMEN1 | |
| SCHEMBL10906079 | 0.71 | ANPEP (0.47) | MEN1KMT2ALMNA | |
| SCHEMBL11432342 | 0.70 | CTSK (0.61) | CTSKCTSSCTSLCTSBMEN1 | |
| SCHEMBL7611741 | 0.70 | ANPEP (0.39) | CTSKCTSSCTSLCTSBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934291-A4 | — | SMITHKLINE BEECHAM CORP (US) | 1999-08-11 | — | — | EP | claimed |
| EP-0934291-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-11 | — | — | EP | claimed |
| WO-1997016433-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-09 | — | — | WO | claimed |