Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.65 |
| ▸ | ACE2 | Q9BYF1 | 9/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6078759 | 0.84 | ACE (0.61) | ACEACE2ELANETSHR | |
| SCHEMBL6078614 | 0.84 | ACE (0.61) | ACEACE2ELANETSHR | |
| SCHEMBL5086307 | 0.80 | HDAC6 (0.49) | ACEACE2 | |
| SCHEMBL2033128 | 0.80 | ACE (0.65) | ACEACE2L3MBTL1LMNAELANE | |
| SCHEMBL6777165 | 0.80 | ACE (0.64) | ACEACE2L3MBTL1LMNATSHR | |
| SCHEMBL11280512 | 0.79 | ACE (1.00) | ACEACE2LMNA | |
| SCHEMBL9705358 | 0.78 | ACE (0.61) | ACEACE2L3MBTL1LMNA | |
| SCHEMBL9705353 | 0.78 | ACE (0.61) | ACEACE2L3MBTL1LMNA | |
| SCHEMBL7381466 | 0.78 | ACE (0.67) | ACEACE2LMNA | |
| SCHEMBL11268988 | 0.77 | ACE (1.00) | ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002050056-A1 | BENZYLAMINE DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-06-27 | — | — | WO | disclosed |