Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.61 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | REN | P00797 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PEPD | P12955 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705358 | 1.00 | ACE (0.61) | ACEACE2L3MBTL1RENKDM4E | |
| SCHEMBL7324427 | 0.85 | ACE (0.57) | ACEACE2L3MBTL1 | |
| SCHEMBL7267775 | 0.81 | ACE (0.54) | ACEACE2RENKDM4EF2 | |
| Methanesulfonamide SCHEMBL10979898 | 0.80 | ACE (0.56) | ACEACE2L3MBTL1RENKDM4E | |
| SCHEMBL10893581 | 0.80 | ACE (0.58) | ACEACE2L3MBTL1RENKDM4E | |
| SCHEMBL10893585 | 0.80 | ACE (0.58) | ACEACE2L3MBTL1RENKDM4E | |
| SCHEMBL7377568 | 0.78 | ACE (0.65) | ACEACE2L3MBTL1LMNA | |
| SCHEMBL7268822 | 0.78 | CMA1 (0.52) | ACERENF2 | |
| SCHEMBL9462523 | 0.78 | ACE (0.51) | ACEACE2RENKDM4EF2 | |
| SCHEMBL29510749 | 0.78 | ACE (0.53) | ACEACE2RENKDM4EF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209643-B1 | PEPTIDE COMPOSITION USEFUL FOR THE MALARIA VACCINE MANUFACTURE AS WELL AS FOR THE PREPARATION OF DIAGNOSTIC KITS FOR THE DETECTION OF MALARIAL DISEASES | ENIRICERCHE S.p.A. (IT) | 1992-07-08 | — | — | EP | disclosed |
| US-4956449-A | Forming polypeptides from tetrapeptides condensed and separated by chromatography | ENIRICERCHE, S.P.A. (IT) | 1990-09-11 | — | — | US | disclosed |
| EP-0209643-A2 | Peptide composition useful for the malaria vaccine manufacture as well as for the preparation of diagnostic kits for the detection of malarial diseases | ENIRICERCHE S.p.A. (IT) | 1987-01-28 | — | — | EP | disclosed |