Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.63 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.63 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.63 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.63 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.63 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.63 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.56 |
| ▸ | CYTH3 | O43739 | 1/20 | 0.56 |
| ▸ | AKT1 | P31749 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372653 | 0.89 | MAPT (0.67) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6029542 | 0.87 | KCNMA1 (0.84) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2605548 | 0.85 | KCNMA1 (0.82) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL18585432 | 0.85 | HTT (0.64) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL20474711 | 0.85 | HTT (0.64) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL31474751 | 0.84 | HTT (0.71) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL31499386 | 0.84 | RAB9A (0.65) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29721840 | 0.83 | RAB9A (0.68) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14351618 | 0.83 | RAB9A (0.68) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL18610467 | 0.82 | SMN1; SMN2 (0.64) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |